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Methiodone (IC-26, WIN 1161-3) is a synthetic opioid analgesic and methadone analogue developed by Sterling Drug Inc. In human studies, low oral doses frequently produced no clear subjective effects, while higher doses induced morphine-like effects with significant inter-individual variability. Twenty-four-hour substitution studies demonstrated that IC-26 effectively suppressed morphine withdrawal, and its addiction liability was concluded to be comparable to morphine.

Dosage

Oral

Common: 10-20mg
Heavy: 35mg+
Light: 5-10mg
Strong: 20-35mg

Duration

Onset: 45-120 minutes
Duration: 6-24 hours
After effects: 6-48 hours

Timeline

Onset
45-120 minutes
Peak
6-24 hours
After
6-48 hours
01.5d3.1d
Typical
Extended range

Effects

AnalgesiaEuphoriaSedationRespiratory depressionMood liftItchinessDry mouthPupil constrictionPhysical relaxation

Avoid

All other CNS depressants.

Half-life

Unknown.

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